Now a group of American researchers have come up with an unusual new technique that has proven its ability to significantly reduce the spread of cancer cells in the body.
scholars’ The results are completely newso they have not yet been subjected to what is called peer review.
The study’s unusual component was brown fat, which the research team on carcinoid tumors injected into lab mice. It was found to prevent cancer from growing.
Brown adipose tissue differs from white adipose tissue in that it burns nutrients such as fat and sugar and converts energy into heat. In the researchers’ study, it was found that brown fat cells got rid of fuel, such as sugar, that cancer cells were using to grow.
Less growth with brown fat
Specifically, the researchers turned white fat cells into brown fat cells by boosting a specific gene in the cells called UCP1.
Next, the researchers injected human breast, prostate, or pancreatic cancer cells into a group of laboratory mice to cause them to develop precancerous tumors.
Around the tumours, the researchers injected either white fat or genetically modified brown fat. It turned out that the tumors that were surrounded by brown fat became less than half the size of the tumors that were surrounded by white fat.
In another part of the study, the researchers implanted genetically modified brown fat into the breasts or pancreas of mice, which had been genetically engineered to cause cancer in those types of tissues.
Here too, the finding was that mice that received brown fat injections around their tumors developed significantly smaller tumors than mice that received injections of white fat.
None of the mice had any direct side effects.
The treatment has been shown to inhibit the growth of cancer cells, but it has not yet eradicated cancer cells.
Therefore, the researchers behind the study are now working further to see if by manipulating other genes in fat cells they can increase the effectiveness of the treatment.
At the same time, the researchers emphasize that in the long term it is important to know how much brown fat to inject to inhibit cancer cells. If you inject too much, you risk brown fat causing excessive weight loss.
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