The funds have equipped the pumps.
This is where the connection with pregnant women comes in.
The researchers looked into the possibility of “starting up” the small purification pumps and getting them up and running again.
The research team knew that the pumps were lined internally with a layer of smooth muscle cells. So they set their sights on the hormone-like substance prostaglandin F2 alpha, which affects smooth muscle cells and is used as a pain trigger to start labor in pregnant women.
As expected, the agent affected lymphangioma tumors in mice. When the researchers injected prostaglandin F2 alpha into older mice, the pumping of impure fluid from the brains of older mice increased to the level normally seen in younger mice.
“Our research shows that by re-establishing the function of the brain’s lymphatic vessels, you can restore a significant portion of the reduced waste removal from the brain that occurs with age. It worked with an agent that is already being used in clinical settings, which means it could potentially become a treatment,” explains Douglas Kelly in one of the papers. press release Which was sent from the University of Rochester.
Douglas Kelly is a professor of mechanical engineering at the same university and one of the researchers who conducted the study.
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