A new study is completely in line with previous studies on FMD (a regimen that mimics fasting) and once again shows that it is effective against cancer. Here you can see ia that periodic FMD can improve the effect of immune response against cancer, increase the proportion of tumors sensitive to immunotherapy, change the microenvironment around tumor, increase treatment effect and reduce side effects of immunotherapy.
What is foot and mouth disease and how does it work against cancer
I previously wrote about what a fasting diet is, ie, foot-and-mouth. And how might fasting and FMD work in cancer?
What is immunotherapy?
The new study shows that fasting makes immunotherapy effective against low-immune breast cancer while reducing side effects.
Immunotherapy improves the prognosis and survival of cancer patients, but despite good results in many types of cancer, the majority of tumors fight it. Combinations of immunotherapy often have serious side effects.
You can read more about immunotherapy here: https://4health.se/?s=Immunotherapy Especially here: https://4health.se/nobelpriset-i-medicin-fiziologi-hur-immunforsvaret-battre-angriper-cancerceller
The new study and FMD in immunotherapy
In the new study, researchers show that a periodic fasting-mimicking diet (FMD) can act on the microenvironment around the tumor and increase the effect of immunotherapy (anti-PD-L1 and anti-OX40) against triple-negative immune impairment. Breast tumors (TNBC). This is by expanding exhausted early T cells, shifting cancer metabolism from glycolytic to respiratory and reducing collagen deposition.
Lots of complicated words here, but if you want to learn more about the specifics of your immune system, please listen to our 279-281 podcast episodes on the topic. I start here: https://4health.se/279-immunforsvaret-sa-funkar-det-del-1-det-ospecifica-medfodda-immunforsvaret
In addition, FMD reduces the incidence of immune-related adverse events (irAEs) by preventing overactivity of the immune response. These results indicate that FMD courses have the potential to improve the effectiveness of the immune response against cancer, increase the proportion of tumors sensitive to immunotherapy and reduce its side effects.
https://pubmed.ncbi.nlm.nih.gov/36001966/
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